Delivery mode and gestational duration decides dynamics of infant gut microbiota

Gut microbiota research has opened a whole now world of our understanding of human physiology right from neuronal functioning to respiratory function to liver function to reproductive functioning.


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As a part of the Growing Up in Singapore Towards healthy Outcomes (GUSTO) study, researchers from Singapore, UK and Nestlé Research Center, Switzerland have found that infant gut bacterial makeup is influenced by external factors such as delivery mode and gestational duration. The study also found that infants with a mature gut bacteria profile at an early age had normal levels of body fat at the age of 18 months, while infants with less mature gut bacteria profiles tended to have lower levels of body fat at the age of 18 months, indicating that gut bacteria could be related to normal development and healthy weight gain.

The study published in mBio shows that most infants had acquired a microbiota profile high in Bifidobacterium and Collinsella by 6 months of age, but the time point of this acquisition was later in infants delivered by caesarean section and those…

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