Stem cell-based therapy offers promise for treatment of type 2 diabetes


In a new study published in the journal Stem Cell Reports, researchers reveal that a combination of stem cell transplantation and anti-diabetic medication was able to successfully treat mice with type 2 diabetes. The findings could set the stage for clinical trials to test the first stem cell-based approach for insulin replacement in patients with type 2 diabetes.

It is estimated that about 400 million people worldwide have diabetes and type 2 diabetes accounts for 90-95% of them. The condition occurs due to inability of the body to produce enough insulin or use it effectively. This results in high blood glucose levels which lead to further secondary complications. It is currently treated with oral medication and/or in combination with insulin injections. This therapy regimen however leads to GI problems, weight gain, extremely low blood glucose or non-responsiveness of patients. To address these complications, senior author Timothy Kieffer of…

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