‘Smart’ insulin discovered: Experimented in mice only

Biotechin.Asia

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An experimental “smart insulin” that acts for 14 hours has shown promise in mice and could be tested in people with type 1 diabetes in two years.

The product, known as Ins-PBA-F and developed by biochemists at the University of Utah, self-activates when blood sugar soars, according to the research published in the Proceedings of the National Academy of Sciences.

Tests on mice with a form of type 1 diabetes showed that one injection could repeatedly and automatically lower blood sugar levels after mice are given amounts of sugar comparable to what they would consume at mealtime. The drug closely mimicked the way the bodies of normal mice would return their blood sugar levels to normal after eating.

People with type 1 diabetes must constantly monitor their blood sugar and manually inject themselves with insulin when needed. Any mistake or lapse can lead to complications, including heart disease, blindness or…

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