The association between gut bacteria and food sensitivity in young children.

Science Translation

Sensitization to food allergens often occurs early in the preschool years. While not all kids who develop food sensitivities end up with full-blown allergies, it is often considered the precursor to the development of allergies and asthma. These conditions are typically grouped together under the term atopic disease because of their tendency to be caused by over active IgE, an antibody in your blood. This IgE latches onto allergens in everyday objects you come in contact with and initiates the allergic response. Atopic diseases include asthma, anaphylaxis and eczema and it is not uncommon for someone with atopic disease to develop all forms of the disease at some point in their life. This is called the atopic march.

Courtesy of LEAP Study, Evelina Children's Hospital, London Courtesy of LEAP Study, Evelina Children’s Hospital, London

One of the leading theories behind the development of atopic diseases, or an over active IgE response, is called the hygiene hypothesis

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